Background: School age children is the critical group because at that age are prone to health problems. The emergence of variety of health problem that often affects school age children (6-12 years old), it’s generally associated with clean and healthy life behavior. Knowledge and attitudes regarding clean and healthy life behavior from an early age to be very supportive in bringing about better health for children in the future.

Objective: To determine the effect knowledge and attitudes toward clean and healthy life behavior in grades 4 and 5 students in SDIT Ibnu Sina.

Methods: This study used a descriptive analytic with cross sectional approach. Sampling technique with total sampling and the total sample are 43 students.

Result :From 43 respondents, There are 12 (27,9%) which have excellent behavior and have excellent knowledge, 11 (25,6%) good knowledge and 4 (9,3%) fairly good knowledge. The effect of attitudes show that there are 21 (48,8%), have excellent attitude and 6 (14,0%) good attitude.

Conclusion:the result of kolmogrov smirnov test obtained p value 0,000 (0,05), there is not significant effect between attitude with clean and healthy life behavior at grades 4 and 5 students in SDIT Ibnu Sina.

Key Words :Knowledge, attitude, Clean and healthy life behavior